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CAS 27848-84-6 Nicergoline

Uses:Nicergoline is a drug used for age-dependent cognitive impairment such as Alzheimers disease and other types of dementia. Nicergoline has shown to protect cultured neurons against β-amyloid toxicity. Nicergoline protects against neuronal cell death induced by activated microglia and astrocytes through the inhibition of inflammatory mediators and the upregulation of neurotrophic factors by glial cells. Nicergoline is a drug used for age-dependent cognitive impairment and it protects cultured neurons against β-amyloid toxicity.

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Product Details

Product Name:Nicergoline

Synonyms:nicergoline Fr.P;10-Methoxy-1,6-dimethylergoline-8β-methanol 5-bromonicotinate;Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 5-bromo-3-pyridinecarboxylate (ester), (8.beta.)-;1,6-Dimethyl-8b-(5-bromonicotinoyloxymethyl)-10a-methoxyergoline;Cergodum;Circo-Maren;Dilasenil;Duracebrol

CAS: 27848-84-6

MF: C24H26BrN3O3

MW:484.39

EINECS:248-694-6

Mol File: 27848-84-6.mol

Melting point :136-138°

Boiling point :594.4±50.0 °C(Predicted)

density :1.3558 (rough estimate)

refractive index :1.6200 (estimate)

storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

solubility Practically insoluble in water, freely soluble in methylene chloride, soluble in ethanol (96 per cent).

form :neat

Pka:6.33±0.40(Predicted)

color :White to Off-White

Water Solubility :Soluble in alcohol, chloroform, and acetone. Insoluble in water

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